Sathish K.N. Yadav

The paper reports cryo-EM structures of the Escherichia coli FtsH periplasmic domain, revealing conformational flexibility and its role in substrate translocation.

The paper uses cryo-EM to analyze membrane proteins, revealing unexpected high-resolution structures of ArnA and AcrB instead of the intended FtsH and YidC complex.

This study identifies UPF2's RNA-binding and unfolding activities, showing its role in stabilizing single-stranded RNA and supporting NMD factor interactions.

This study shows that cargo-sensitive TPR switch in kinesin-1 controls its conformational dynamics by dislocating the TPR shoulder, promoting motor domain activation and microtubule binding.

The paper engineers ADDobody protein scaffolds to generate high-avidity ADDomer super-binders through genetic modification and structural validation.

This study investigates how the BriS{Delta} variant of SARS-CoV-2 affects spike structure, function, and infectivity across different cell types.

The paper designs and validates de novo proteins with single and multi-heme binding capabilities, achieving atomic-level structural resolution for functional engineering.