Mapping the Transcriptional Landscape of Drug Responses in Primary Human Cells Using High-Throughput DRUG-seq
Lauren M. Baugh, Sébastien Vigneau, Srijani Sridhar, Sarah A. Boswell, George Pilitsis, John Bradley, Olga Allen, Laura M. Rand, Amanda Riccardi, Kelsey Roach, Kevin Lema, Ayla Ergün
The paper develops DRUG-seq to profile drug responses in primary human cells, revealing shared and cell-type-specific transcriptional changes across multiple compounds and concentrations.
bioRxiv · Jun 3, 2025 · PreprintSystems Biology