Author

Laura M. Rand

Ginkgo Bioworks, Inc. (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Research Focus:benchmarking· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Organism:Drosophila· 1

Frequent Co-Authors

Aanal BhattiD· 2 shared Alexander SmithiD· 2 shared Ammar ArsiwalaiD· 2 shared Blake Harris· 2 shared David W. BorhaniiD· 2 shared Joshua MolleriD· 2 shared Lucía Daniela GrippoiD· 2 shared Peter M. TessieriD· 2 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersBiophysics

Aanal BhattORCID

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Author profile →

4 papers

Recent·Most cited

Predicting VHH-Fc Developability from Large-Scale IgG Data

Joshua Moller, Seth Ritter, Laura M. Rand, Alexander Smith, Yolaine Pierre, Tim Bloomingdale, Blake Harris, Sai Karthick, Lucía Daniela Grippo, Aanal Bhatt, Jay Patel, Xiang Ao, Rebecca Bhatt, Rich Cohen, David W. Borhani, , Ammar Arsiwala

The paper introduces a dataset of VHH-Fc antibodies and shows that IgG-trained models outperform VHH-Fc-specific models in predicting developability properties.

bioRxiv · Aug 21, 2026 · PreprintBiophysics

Decoding Bispecific Antibody Developability: Design Rules and Predictive Models from a 160-Member Library

Seth Ritter, Laura M. Rand, Sai Karthick, Tim Bloomingdale, Alexander Smith, Xiang Ao, Yolaine Pierre, Blake Harris, Joshua Moller, Aanal Bhatt, Rebecca Bhatt, Jay Schwartz, Lucía Daniela Grippo, Rich Cohen, David W. Borhani, , Ammar Arsiwala

This paper analyzes 160 bispecific antibodies and their parental arms to identify developability inheritance patterns and predictive models for bispecific antibody design.

bioRxiv · Jun 19, 2026 · PreprintBiophysics

Mapping the Transcriptional Landscape of Drug Responses in Primary Human Cells Using High-Throughput DRUG-seq

Lauren M. Baugh, Sébastien Vigneau, Srijani Sridhar, Sarah A. Boswell, George Pilitsis, John Bradley, Olga Allen, Laura M. Rand, Amanda Riccardi, Kelsey Roach, Kevin Lema, Ayla Ergün

The paper develops DRUG-seq to profile drug responses in primary human cells, revealing shared and cell-type-specific transcriptional changes across multiple compounds and concentrations.

bioRxiv · Jun 3, 2025 · PreprintSystems Biology

Glia-neuron signaling mediated by two different BMP ligands impacts synaptic growth

Mathieu Bartoletti, Tracy Knight, Aaron Held, Laura M. Rand, Kristi A. Wharton

This study identifies two BMP ligands, Gbb and Dpp, that mediate bidirectional glia-neuron signaling to regulate synaptic growth in Drosophila.

bioRxiv · Feb 23, 2021 · PreprintNeuroscience