High Content Screening and Proteomic Analysis Identify a Kinase Inhibitor that rescuespathological phenotypes in a Patient-Derived Model of Parkinson's Disease
Nasia Antoniou, Kanella Prodromidou, Georgia Kouroupi, Ioanna Boumpoureka, Martina K. Samiotaki, George Panayotou, Maria Xilouri, Ismini Kloukina, Leonidas Stefanis, Régis Grailhe, Era Taoufik, Rebecca Matsas
The paper identifies a kinase inhibitor, BX795, that rescues pathological phenotypes in a patient-derived Parkinson's disease model through proteomic analysis and high-content screening.
npj Parkinson s Disease · Feb 11, 2022Peer-reviewedNeuroscience