Author

Georgina Agyei

University of Notre Dame

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Organism:fungi (other)· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Felipe Hiram Santiago-TiradoiD· 2 shared Peter V. StuckeyiD· 2 shared Armando M. MarrufoiD· 1 shared Christopher J. WinskiiD· 1 shared Federico J Celis· 1 shared Kayla C Anderson· 1 shared Robbi L. RossiD· 1 shared Sarah Chapman· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

Felipe Hiram Santiago-TiradoORCID

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2 papers

Recent·Most cited

Set202 is a histone lysine methyltransferase that enables Cryptococcus neoformans to adapt to the host environment

Georgina Agyei, Kayla C Anderson, Peter V. Stuckey, Federico J Celis, Timothy J. Theisen, Felipe Hiram Santiago-Tirado

This paper identifies Set202 as a histone methyltransferase in Cryptococcus neoformans that enables adaptation to host conditions by modifying gene expression through epigenetic mechanisms.

bioRxiv · Sep 18, 2026 · PreprintMicrobiology

Lack of an atypical PDR transporter generates an immunogenic Cryptococcus neoformans strain that drives a dysregulated and lethal immune response in murine lungs

Christopher J. Winski, Peter V. Stuckey, Armando M. Marrufo, Georgina Agyei, Robbi L. Ross, Tamanna Urmi, Sarah Chapman, Felipe Hiram Santiago-Tirado

This study shows that the absence of PDR6 in Cryptococcus neoformans leads to a hyper-inflammatory immune response in mice, causing immune-dependent tissue damage and death rather than fungal burden.

mBio · May 30, 2025Peer-reviewedMicrobiology