Armando M. Marrufo

The paper identifies a T2/T17 immune signature in individuals with persistent respiratory symptoms linked to airborne pollutant exposure and small-airway dysfunction.

This study identifies the Efg1 regulon active in C. albicans during growth in human urine, validates its clinical relevance in catheter samples, and characterizes key downstream factors involved in fungal CAUTI.

This study shows that the absence of PDR6 in Cryptococcus neoformans leads to a hyper-inflammatory immune response in mice, causing immune-dependent tissue damage and death rather than fungal burden.

This study shows that fibrin accumulation in a catheterized bladder promotes anti-inflammatory macrophage polarization, which impairs antimicrobial responses and allows bacterial persistence in UTIs.