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Georgy Chistov

King Abdullah University of Science and Technology

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Synthetic Biology· 1

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Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:plant (other)· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1

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Anandsukeerthi SandholuiD· 1 shared Brandon HuntingtoniD· 1 shared Israa Salem· 1 shared Jun WangiD· 1 shared Junrui ZhangiD· 1 shared Stefan T. AroldiD· 1 shared

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Synthetic BiologyHeliyonPeer-reviewedJul 1, 2024

P-NADs: PUX-based NAnobody Degraders for Ubiquitin-Independent Degradation of Target Proteins

Jun Wang, Georgy Chistov, Junrui Zhang…·Stefan T. Arold

This paper introduces P-NADs, a ubiquitin-independent protein degradation method using PUX-adaptor proteins and nanobodies, demonstrating their efficacy in human cells and potential for therapeutic applications.

2 citations

humanplant (other)

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