Spatiotemporal regulation of the hepatocyte growth factor receptor MET activity by sorting nexins 1 and 2 in HCT116 colorectal cancer cells
Laiyen García Delgado, Amélie Derome, Samantha Longpré, Marilyne Giroux-Dansereau, Ghenwa Basbous, Christine L. Lavoie, Caroline Saucier, Jean‐Bernard Denault
This study shows that SNX1 and SNX2 regulate MET trafficking, affecting phosphorylation of MET and AKT but not ERK1/2, and influence apoptosis resistance in CRC cells.
Bioscience Reports · Jun 1, 2024Peer-reviewedCancer Biology