Author

Amélie Derome

Université de Sherbrooke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

Caroline SaucieriD· 2 shared Christine L. LavoieiD· 2 shared Jean‐Bernard DenaultiD· 2 shared Laiyen García DelgadoiD· 2 shared Ghenwa Basbous· 1 shared Marilyne Giroux-Dansereau· 1 shared Samantha Longpré· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

Caroline SaucierORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 7, 2026

SNX2, but not SNX1, regulates the hepatocyte growth factor receptor MET in HCT116 colorectal cancer cells

Laiyen García Delgado, Amélie Derome, Christine L. Lavoie…·Jean‐Bernard Denault

This study shows that SNX2, but not SNX1, regulates MET endosomal trafficking and signaling in HCT116 cells, leading to enhanced AKT activation and poorer CRC patient survival.

DOI 10.64898/2026.10.06.755412

humanexperimental assay

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Cancer BiologyBioscience ReportsPeer-reviewedJun 1, 2024

Spatiotemporal regulation of the hepatocyte growth factor receptor MET activity by sorting nexins 1 and 2 in HCT116 colorectal cancer cells

Laiyen García Delgado, Amélie Derome, Samantha Longpré…·Jean‐Bernard Denault

This study shows that SNX1 and SNX2 regulate MET trafficking, affecting phosphorylation of MET and AKT but not ERK1/2, and influence apoptosis resistance in CRC cells.

2 citations

humanproteomics

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