The lncRNA FENDRR fine-tunes FOXF1 protein levels through a negative feedback loop governing human embryonic lung fibroblast-to-myofibroblast transition
Jean-Francois Laurendeau, Sophie Mockly, Gilberto Duran-Bishop, Sophie Ehresmann, Elena Goretti, Virginie Calderon, Mohan K. Malleshaiah, Martin Sauvageau
The paper identifies a negative feedback loop between lncRNA FENDRR and FOXF1 that regulates protein levels during fibroblast-to-myofibroblast transition in lung development.
bioRxiv · Apr 12, 2026 · PreprintMolecular Biology