Ileitis abolishes tolerogenic functions of the enterohepatic bile acid pool
Zhiping Xiao, Kôichi Sudô, Amber Delmas Eliason, Jiabao Liu, Paola Munoz‐Tello, Henry D. Dionne, Fiona Nguyen, Alexander D. Hondros, 楊惠娟, B. JoNell Hamilton, Akshaya Balasubramanian, Courtney Lynn Hegner, Gilian Jacobsen, Erin M. Tonzi, Ila K. Kaul, , Mark S. Sundrud
The paper shows that ileitis disrupts bile acid (BA) pool balance, altering immune regulation by affecting BA receptor interactions and Th17 cell function.
bioRxiv · Sep 18, 2026 · PreprintImmunology