The Porphyromonas gingivalis lipid A 1-phosphatase LpxE has unique features and requires a functional type IX secretion system for its activity
Sunjun Wang, Yichao Liu, Beichang Zhang, Joseph Aduse‐Opoku, Roberto Buccafusca, Oscar Ayrton, Giulia Mastroianni, Pedro Machado, Mark A. J. Roberts, Michael A. Curtis, James A. Garnett
This study investigates the role of T9SS OMPs in OMV biogenesis and shows that LpxE, a lipid A 1-phosphatase, requires these proteins for activity and correct vesicle formation.
Journal of Oral Microbiology · Dec 14, 2025Peer-reviewedMicrobiology