Michael A. Curtis

Hepatic Xanthine Oxidoreductase Sustains Antithrombotic Nitric Oxide Signalling Through the Nitrate-Nitrite-Nitric Oxide Pathway

This study shows that hepatic xanthine oxidoreductase (XOR) sustains antithrombotic nitric oxide signaling through the nitrate-nitrite-NO pathway, and dietary nitrate can restore this signaling when endothelial NO is deficient.

The Porphyromonas gingivalis lipid A 1-phosphatase LpxE has unique features and requires a functional type IX secretion system for its activity

This study investigates the role of T9SS OMPs in OMV biogenesis and shows that LpxE, a lipid A 1-phosphatase, requires these proteins for activity and correct vesicle formation.

Hemin availability induces coordinated DNA methylation and gene expression changes in Porphyromonas gingivalis

This study investigates how hemin availability affects DNA methylation and gene expression in Porphyromonas gingivalis, identifying coordinated changes in six genes related to virulence.