Activation of PIEZO1 Inhibits Kidney Cystogenesis
Qingfeng Fan, Mohamad Hadla, Zack Peterson, Grace Nelson, Hong Ye, Xiaofang Wang, Jean Marc Mardirossian, Peter C. Harris, Seth L. Alper, Y. S. Prakash, Arthur Beyder, Vicente E. Torres, Fouad T. Chebib
This study shows that activating PIEZO1 reduces cyst formation in kidney cells and ex vivo models, suggesting it could be a therapeutic target for ADPKD.
Kidney360 · Oct 2, 2024Peer-reviewedCell Biology