Arthur Beyder

This study shows that intestinal macrophages have region-specific trophic requirements and neuroimmune functions, with CSF1 playing a key role in small-intestinal nitrergic neuron-macrophage interactions.

This study identifies maladaptive Piezo1 mechanotransduction as a driver of smooth muscle aging in the gut, showing it impairs contractility and contributes to gastrointestinal dysfunction.

This study identifies C1qa⁺ muscularis macrophages as regulators of enteric synaptic homeostasis and gastrointestinal motility through complement-dependent mechanisms.

This study identifies PIEZO1-mediated mechanosensation as a mechanism linking aging to bladder dysfunction and proposes dietary intervention as a non-invasive strategy.

This study shows that reducing Hv1 proton channels in macrophages improves antigen presentation and anti-tumor responses in glioma by altering macrophage behavior and immune response.

This study shows that activating PIEZO1 reduces cyst formation in kidney cells and ex vivo models, suggesting it could be a therapeutic target for ADPKD.

The paper shows that PIEZO2 in dorsal root ganglia neurons regulates gut motility by sensing mechanical stretch, affecting gastrointestinal transit.

This study performs a genome-wide association analysis of hemorrhoidal disease in 944,133 individuals, identifying 102 risk loci and linking them to vascular and tissue development pathways.