HIV inhibits Warburg metabolism in human macrophages infected with Mycobacterium tuberculosis.
Kevin Edward Brown, Aaron M. Walsh, Anjali S Yennemadi, Dearbhla M Murphy, Sarah A. Connolly, Grainne Jameson, Mary P. O’Sullivan, Sharee A. Basdeo, Seónadh M. O’Leary, Gina R. Leisching, Joseph Keane
This study shows HIV-1 infection suppresses Mtb-induced glycolytic reprogramming in macrophages, altering immunometabolic responses and increasing TB susceptibility.
Scientific Reports · May 7, 2026Peer-reviewedImmunology