Author

Gunjandeep Singh

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew A. SprouliD· 2 shared Andrew F. TeichiD· 2 shared Christopher L. CardonaiD· 2 shared Ellen AngelesiD· 2 shared Ronak PateliD· 2 shared Alejandro ChaveziD· 1 shared Aleyda Maldonado· 1 shared Angel L. Piriz· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Andrew A. SproulORCID

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2 papers

Recent·Most cited

Reduced SH3RF3 may protect against Alzheimer's disease by lowering microglial pro-inflammatory responses via modulation of JNK and NFkB signaling

Ronak Patel, Rong Cheng, Christopher L. Cardona, Ellen Angeles, Gunjandeep Singh, Sabrina Miller, Archana Ashok, Andrew F. Teich, Angel L. Piriz, Aleyda Maldonado, Ivonne Z. Jiménez‐Velázquez, Richard P Mayeux, Joseph H. Lee, Andrew A. Sproul

The paper identifies protective SH3RF3 variants that delay Alzheimer's onset by reducing microglial inflammation through JNK and NFkB pathway modulation in PSEN1G206A carriers.

Glia · May 27, 2026Peer-reviewedNeuroscience

High throughput identification of genetic regulators of microglial inflammatory processes in Alzheimer's disease

Christopher L. Cardona, Lai Wei, Joonwon Kim, Ellen Angeles, Gunjandeep Singh, Shiye Chen, Ronak Patel, Nkechime Ifediora, Peter Canoll, Andrew F. Teich, Gunnar Hargus, Alejandro Chavez, Andrew A. Sproul

This study identifies genetic regulators of microglial inflammation in Alzheimer's disease using CRISPRi screens and scRNA-seq, revealing key genes that modulate inflammatory states and disease-relevant clusters.

Journal of Neuroinflammation · Dec 3, 2025Peer-reviewedNeuroscience