Efficient Reprogramming of the Epiblast Enables the Generation of Cloned Mice
Guomeng Li, Wandong Bao, Mei Hu, Heng Xie, Lianwei Li, Jianlin Xu, Shu Wei, Yue Teng, Yanyan Zhang, Yunan Chen, Lin Ran, Jiawen Liu, Juan Du, Muhammad Ameen Jamal, Zhanshan (Sam) Ma, , Jiangwei Lin
The paper shows that efficient reprogramming in SCNT occurs exclusively in the epiblast, enabling cloned mouse generation through a lineage-specific mechanism.
bioRxiv · Mar 14, 2026 · PreprintDevelopmental Biology