Author

H Zhang

Changchun University of Chinese MedicinePrimary ORCID profile (0000-0002-1755-4494 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

H ZhangiD1 paper · Albert Einstein College of Medicine

Biology Disciplines

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Immunology· 2 Bioinformatics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:protein structure· 2 Research Focus:batch correction / integration· 1

Frequent Co-Authors

Alzheimer’s Disease Neuroimaging Initiative· 1 shared Andrea L. CoxiD· 1 shared Andrew I. FlyakiD· 1 shared Antony Simons· 1 shared B Choudhury· 1 shared Catherine F. Slattery· 1 shared Christopher S ParkeriD· 1 shared Daqing ZhaoiD· 1 shared

Activity by Year

2021-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperNeuroscience

Alzheimer’s Disease Neuroimaging Initiative

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Author profile →

5 papers

Recent·Most cited

Cycle-consistent deep generative modeling unifies cellular states across unpaired spatial and single-cell modalities

H Zhang, Jeffrey F. Quinn, Data Science Teamlab, Wesley Tansey

MultiTME integrates spatial and single-cell data using a cycle-consistent deep generative model, revealing a spatially coherent tumor axis in colorectal cancer.

bioRxiv · May 26, 2026 · PreprintBioinformatics

Structure and function of human NXPE1, a sialic acid O-acetyltransferase

H Zhang, F Li, M Zhang, Hiroyasu Konno, Wei Yu, X Min, Mousumi Paulchakrabarti, B Choudhury, Antony Simons, Derek E. Piper, H Hsu, Wenjun Ouyang

This study determines the cryo-EM structure of human NXPE1, identifies it as a sialic acid O-acetyltransferase, and shows its role in intestinal barrier function relevant to IBD.

bioRxiv · May 22, 2026 · PreprintImmunology

mAbClust with AlphaFold 3 avoids hallucinations to define a quaternary broadly neutralizing HCV epitope

Harry T. Paul, Jessica L. Mimms, Hanna Aboueid, Laura S. Sánchez B., Liudmila Kulakova, Xander E. Wilcox, Katrina Kuhn, H Zhang, Eric A. Toth, Nicole Skinner, Andrew I. Flyak, Gilad Ofek, H. Benjamin Larman, Thomas R. Fuerst, Stuart C. Ray, , Justin R. Bailey

The paper isolates E1-dependent broadly neutralizing antibodies against HCV and uses mAbClust with AlphaFold 3 to map a quaternary epitope spanning E1 and E2.

bioRxiv · Jan 7, 2026 · PreprintImmunology

SF3A2 deacetylation at lysin 10 mitigates myocardial pathological remodeling by reprogramming cardiomyocyte metabolism

Renpeng Guo, Zepeng Zhang, H Zhang, Yue Jin Yang, Ming Qiao, J Zhang, Y Wang, Jinjin Chen, Jing Li, Mingxia Wu, Kexin Yang, Yangyang Qing, Haisi Dong, Xiangyan Li, Daqing Zhao, Qingxia Huang

This study shows that SF3A2 deacetylation at K10 reduces myocardial remodeling by altering cardiomyocyte metabolism, including glucose and fatty acid metabolism.

bioRxiv · Dec 27, 2025 · PreprintMolecular Biology

Not all voxels are created equal: reducing estimation bias in regional NODDI metrics using tissue-weighted means

Christopher S Parker, Thomas D. Veale, Martina Bocchetta, Catherine F. Slattery, Ian B. Malone, David Lee Thomas, Jonathan M. Schott, David M. Cash, H Zhang, Alzheimer’s Disease Neuroimaging Initiative

This paper introduces a tissue-weighted mean method to reduce bias in NODDI metrics by accounting for CSF partial volume, showing it improves accuracy in ROI analysis for neurodegenerative disease studies.

NeuroImage · Nov 28, 2021Peer-reviewedNeuroscience