Author

Jessica L. Mimms

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Justin R. BaileyiD· 3 shared Andrew I. FlyakiD· 2 shared Xander E. WilcoxiD· 2 shared Alexandra A. Abu-ShmaisiD· 1 shared Alexis K. JankeiD· 1 shared Andrea L. CoxiD· 1 shared Barton F. HaynesiD· 1 shared Bethany N. Howard· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

Justin R. BaileyORCID

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Author profile →

3 papers

Recent·Most cited

Structural Repertoire of HCV Broadly Neutralizing Antibodies Targeting the E2 Front Layer Supersite

Xander E. Wilcox, Rajat Punia, Jessica L. Mimms, Nicole Frumento, Justin R. Bailey, Andrew I. Flyak

This study classifies three structural classes of HCV broadly neutralizing antibodies targeting the E2 front layer supersite and shows their sensitivity to viral polymorphisms.

Structure · Feb 2, 2026Peer-reviewedImmunology

mAbClust with AlphaFold 3 avoids hallucinations to define a quaternary broadly neutralizing HCV epitope

Harry T. Paul, Jessica L. Mimms, Hanna Aboueid, Laura S. Sánchez B., Liudmila Kulakova, Xander E. Wilcox, Katrina Kuhn, H Zhang, Eric A. Toth, Nicole Skinner, Andrew I. Flyak, Gilad Ofek, H. Benjamin Larman, Thomas R. Fuerst, Stuart C. Ray, , Justin R. Bailey

The paper isolates E1-dependent broadly neutralizing antibodies against HCV and uses mAbClust with AlphaFold 3 to map a quaternary epitope spanning E1 and E2.

bioRxiv · Jan 7, 2026 · PreprintImmunology

Glycan-reactive antibodies isolated from human HIV-1 vaccine trial participants show broad pathogen cross-reactivity

Parker J. Jamieson, Xiaoying Shen, Alexandra A. Abu-Shmais, Perry T. Wasdin, Katarzyna Janowska, Robert J. Edwards, Garrett Scapellato, Maurice Bukenya, Lindsay E Bass, Simone I. Richardson, Nelia P. Manamela, Shuying Liu, Maggie Barr, Lindsey Adams, Cristina Paola Velez-Castro, , Ivelin S. Georgiev

The paper isolates glycan-reactive antibodies from HIV-1 vaccine trial participants and finds they neutralize diverse HIV strains and show broad cross-reactivity against other pathogens.

Journal of Virology · Nov 10, 2025Peer-reviewedImmunology