Andrea L. Cox

Human resistin is critical to activation of the NLRP3 inflammasome in macrophages

This study identifies hResistin's role in priming and activating the NLRP3 inflammasome in macrophages, linking it to inflammatory diseases through HMGB1, BTK, and downstream cytokine production.

mAbClust with AlphaFold 3 avoids hallucinations to define a quaternary broadly neutralizing HCV epitope

The paper isolates E1-dependent broadly neutralizing antibodies against HCV and uses mAbClust with AlphaFold 3 to map a quaternary epitope spanning E1 and E2.

Mechanisms of sex differences in acute and long COVID sequelae in mice

This study identifies sex differences in long COVID sequelae in mice, showing that X-linked genes like Xist and Tlr7 contribute to persistent inflammation and cognitive impairments in females.

A Third COVID-19 Vaccine Dose in Kidney Transplant Recipients Induces Antibody Response to Vaccine and Omicron Variants but Shows Limited Ig Subclass Switching

This study evaluates antibody responses to a third dose of COVID-19 vaccine in kidney transplant recipients, finding reduced neutralizing antibodies and altered IgG subclass switching compared to healthy controls.