Author

M. S. Cohen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Ashworth· 1 shared A. Dey· 1 shared A. Ogbe· 1 shared A. R. Fehr· 1 shared B. F. Haynes· 1 shared C. B. Smith· 1 shared C. Brenner· 1 shared C. D. Heer· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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1 shared paperCancer Biology

A. Ashworth

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation

T. H. Pham, K. B. Pahuja, T. J. Hagenbeek, J. Zbieg, C. L. Noland, V. C. Pham, X. Yao, C. M. Rose, K. C. Browder, H.-J. Lee, M. Yu, M. Liang-Chu, S. E. Martin, E. Verschueren, J. Li, , A. Dey

This study identifies RNF146 as an E3 ubiquitin ligase that degrades TEAD proteins via the proteasome, showing that pharmacological induction of TEAD ubiquitination can suppress YAP/TAZ-driven cancer growth.

bioRxiv · Oct 3, 2023 · PreprintCancer Biology

A sort-seq approach to the development of single fluorescent protein biosensors

J. N. Koberstein, M. L. Stewart, T. L. Mighell, C. B. Smith, M. S. Cohen

This paper introduces a sort-seq method to optimize single fluorescent protein biosensors by testing variants in parallel, identifying high-dynamic-range variants and improved linker sequences.

bioRxiv · Aug 21, 2020Biochemistry

Deep Sequencing Reveals Compartmentalized HIV-1 in the Semen of Men with and without STI-associated Urethritis

O. D. Council, S. Zhou, C. D. McCann, I. Hoffman, G. Tegha, D. Kamwendo, M. Matoga, S. L. Kosakovsky Pond, M. S. Cohen, R. Swanstrom

This study examines HIV-1 compartmentalization in semen of men with and without STI-associated urethritis, finding stable viral populations and limited replication despite STI treatment.

Journal of Virology · Jun 1, 2020Peer-reviewedMicrobiology

Coronavirus infection and PARP expression dysregulate the NAD Metabolome: an actionable component of innate immunity

C. D. Heer, D. J. Sanderson, L. S. Voth, Y. M. O. Alhammad, M. S. Schmidt, S. A. J. Trammell, S. Perlman, M. S. Cohen, A. R. Fehr, C. Brenner

This study shows that SARS-CoV-2 infection upregulates MARylating PARPs and NAD synthesis enzymes, and that enhancing NAD levels can reduce viral replication.

bioRxiv · Apr 17, 2020Microbiology

Subordinate effect of -21M HLA-B dimorphism on NK cell repertoire diversity and function in HIV-1 infected individuals of African origin

E. Moreno Cubero, A. Ogbe, M. S. Cohen, B. F. Haynes, P. Borrow, D. Peppa

This study examines the effect of HLA-B -21M dimorphism on NK cell diversity and function in HIV-1/HCMV co-infected African individuals, finding no significant correlation with HLA-E abundance or functional advantage.

bioRxiv · Sep 30, 2019Immunology