Author

H. D. Basavarajappa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Organism:mouse· 1

Frequent Co-Authors

P. T. Fueger· 2 shared A. J. Lutkewitte· 1 shared J. M. Irimia· 1 shared Y.-C. Chen· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 4 mutual co-author links

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2 shared papersCell Biology

P. T. Fueger

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2 papers

Recent·Most cited

Glucolipotoxicity-induced Mig6 desensitizes EGFR signaling and promotes pancreatic beta cell death

Y.-C. Chen, A. J. Lutkewitte, H. D. Basavarajappa, P. T. Fueger

This study shows that Mig6, induced by glucolipotoxicity, inhibits EGFR signaling and promotes beta cell death in type 2 diabetes.

bioRxiv · Nov 24, 2020Cell Biology

The adaptor protein NumbL is involved in the control of glucolipotoxicity-induced pancreatic beta cell apoptosis

H. D. Basavarajappa, J. M. Irimia, P. T. Fueger

This study identifies NumbL as a mediator of glucolipotoxicity-induced beta cell apoptosis by interacting with Mig6 and TRAF6 to activate NF-κB signaling.

bioRxiv · Aug 16, 2020Biochemistry