Author

H. Davaapil

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:drug response / drug discovery· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. Sinha· 4 shared A. G. Jacob· 2 shared A. A. Guy· 1 shared A. Child· 1 shared A. E. Markaki· 1 shared A. Granata· 1 shared A. Ross· 1 shared A. Stavropoulou-Tatla· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersCell Biology

S. Sinha

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Differentiation and quality control of smooth muscle cells from human pluripotent stem cells via the neural crest lineage

P. J. Holt, H. Davaapil, D. K. Shetty, A. G. Jacob, S. Sinha

This paper describes a protocol to differentiate human pluripotent stem cells into vascular smooth muscle cells via the neural crest lineage and outlines quality control steps.

bioRxiv · May 31, 2023 · PreprintCell Biology

A phenotypic screen of Marfan syndrome iPSC-derived vascular smooth muscle cells uncovers GSK3β as a new target

H. Davaapil, M. McNamara, A. Granata, R. G. C. Macrae, M. Hirano, M. Fitzek, J. A. Aragon-Martin, A. Child, D. M. Smith, S. Sinha

The paper screens small molecules in MFS patient-derived VSMCs to identify GSK3β as a novel therapeutic target for aortic disease.

bioRxiv · Apr 11, 2022Cell Biology

Regenerative and non-regenerative transcriptional states of the human epicardium: from foetus to adult and backagain

V. R. Knight-Schrijver, H. Davaapil, A. Ross, X. He, L. Vallier, L. Gambardella, S. Sinha

This study compares foetal and adult human epicardium using single-cell RNA sequencing to identify regenerative programs and their absence in adults, suggesting ways to enhance cardiac regeneration.

bioRxiv · Oct 11, 2021Cell Biology

Densified Collagen Tubular Grafts for Human Tissue Replacement and Disease Modelling Applications

A. W. Justin, F. Cammarata, A. A. Guy, S. R. Estevez, S. Burgess, H. Davaapil, A. Stavropoulou-Tatla, J. Ong, A. G. Jacob, K. Saeb-Parsy, S. Sinha, A. E. Markaki

This paper develops a cell-free, densified collagen tubular graft that is mechanically strong, customizable, and supports cell incorporation for tissue replacement and disease modeling.

bioRxiv · Feb 5, 2021Bioengineering