Author

A. Granata

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. Sinha· 2 shared A. Child· 1 shared C. Vilain· 1 shared D. M. Smith· 1 shared H. Davaapil· 1 shared H. S. Markus· 1 shared J. A. Aragon-Martin· 1 shared K. Horsburgh· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

S. Sinha

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Author profile →

2 papers

Recent·Most cited

A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases in extracellular matrix abnormalities

M. Al-Thani, M. Goodwin-Trotman, S. Bell, K. Patel, L. K. Fleming, C. Vilain, M. Abramowicz, S. M. Allan, T. Wang, Z. Cader, K. Horsburgh, T. Van Agtmael, S. Sinha, H. S. Markus, A. Granata

This paper develops a human iPSC model of COL4A1/A2 small vessel disease, showing that MMP inhibition rescues ECM abnormalities and mural cell defects.

bioRxiv · Feb 23, 2023 · PreprintCell Biology

A phenotypic screen of Marfan syndrome iPSC-derived vascular smooth muscle cells uncovers GSK3β as a new target

H. Davaapil, M. McNamara, A. Granata, R. G. C. Macrae, M. Hirano, M. Fitzek, J. A. Aragon-Martin, A. Child, D. M. Smith, S. Sinha

The paper screens small molecules in MFS patient-derived VSMCs to identify GSK3β as a novel therapeutic target for aortic disease.

bioRxiv · Apr 11, 2022Cell Biology