From 1D sequence to 3D chromatin dynamics and cellular functions: a phase separation perspective
S. Liu, L. Zhang, H. Quan, H. Tian, L. Meng, L. Yang, H. Feng, Y. Q. Gao
The paper identifies forest and prairie genomic domains based on CpG island density and shows their role in shaping cell-type-specific chromatin structures and genomic properties through phase separation mechanisms.
bioRxiv · Jan 28, 2018Biophysics