Author

H. Hata

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:simulation· 1

Frequent Co-Authors

A. Kitao· 1 shared F. Yokoyama· 1 shared H. Fukuyama· 1 shared I. Kawagishi· 1 shared M. Nishiyama· 1 shared N. Kumar· 1 shared O. Ohara· 1 shared T. Hasegawa· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

A. Kitao

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Author profile →

2 papers

Recent·Most cited

Development of a new genotype-phenotype linked antibody screening system

T. Watanabe, H. Hata, Y. Mochizuki, F. Yokoyama, T. Hasegawa, N. Kumar, T. Kurosaki, O. Ohara, H. Fukuyama

This paper develops a new antibody screening system using a Golden Gate-based dual-expression vector to rapidly isolate high-affinity cross-reactive antibodies from immunized mice.

bioRxiv · Mar 6, 2024Bioengineering

High pressure inhibits signaling protein binding to the flagellar motor and bacterial chemotaxis through enhanced hydration

H. Hata, Y. Nishihara, M. Nishiyama, Y. Sowa, I. Kawagishi, A. Kitao

This study investigates how high pressure affects CheYp-FliM binding in E. coli chemotaxis using molecular dynamics and microscopy, finding that pressure weakens binding by ~10 kcal/mol and inhibits motor reversal.

bioRxiv · Sep 9, 2019Biophysics