Author

H. I. Zgurskaya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:experimental assay· 2 Approach:mechanistic / dynamical model· 2 Assay:proteomics· 2 Organism:Arabidopsis· 1 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

I. V. Leus· 2 shared V. RYBENKOV· 2 shared A. Bosin· 1 shared A. J. Higgins· 1 shared A. S. Duerfeldt· 1 shared A. V. Vargiu· 1 shared B. Chandar· 1 shared B. Russell Lewis· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

I. V. Leus

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintJun 1, 2023

Molecular determinants of avoidance and inhibition of Pseudomonas aeruginosa MexB efflux pump

S. Gervasoni, J. Mehla, C. Bergen…·H. I. Zgurskaya

This study investigates how different compounds interact with the MexB efflux pump of Pseudomonas aeruginosa, revealing distinct interaction patterns that distinguish inhibitors from substrates.

DOI 10.1101/2023.06.01.543207

bacteria (other)proteomics

𝕏 PostBluesky

BiochemistrybioRxivDec 9, 2022

Conformational restriction shapes inhibition of a multidrug efflux adaptor protein

B. Russell Lewis, M. R. Uddin, M. Moniruzzaman…·E. Reading

The paper investigates how an inhibitor restricts the conformational dynamics of AcrA, a multidrug efflux adaptor protein, to block drug signal transmission in E. coli.

DOI 10.1038/s41467-023-39615-x

E. coliproteomics

𝕏 PostBluesky

MicrobiologybioRxivJun 27, 2022

Structure-Uptake Relationship Studies of Oxazolidinones in Gram-negative ESKAPE Pathogens

Z. Hu, I. V. Leus, B. Chandar…·A. S. Duerfeldt

This study investigates how structural changes in oxazolidinones affect their permeation and activity in Gram-negative bacteria, identifying analogs with broad-spectrum activity.

DOI 10.1021/acs.jmedchem.2c01349

E. coliArabidopsis

𝕏 PostBluesky