Author

I. V. Leus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 1 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

H. I. Zgurskaya· 2 shared V. RYBENKOV· 2 shared A. Bosin· 1 shared A. S. Duerfeldt· 1 shared A. V. Vargiu· 1 shared B. Chandar· 1 shared B. Sherborne· 1 shared C. Bergen· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMicrobiology

H. I. Zgurskaya

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2 papers

Recent·Most cited

Molecular determinants of avoidance and inhibition of Pseudomonas aeruginosa MexB efflux pump

S. Gervasoni, J. Mehla, C. Bergen, I. V. Leus, E. Margiotta, G. Malloci, A. Bosin, A. V. Vargiu, O. Lomovskaya, V. RYBENKOV, P. Ruggerone, H. I. Zgurskaya

This study investigates how different compounds interact with the MexB efflux pump of Pseudomonas aeruginosa, revealing distinct interaction patterns that distinguish inhibitors from substrates.

bioRxiv · Jun 1, 2023 · PreprintMicrobiology

Structure-Uptake Relationship Studies of Oxazolidinones in Gram-negative ESKAPE Pathogens

Z. Hu, I. V. Leus, B. Chandar, B. Sherborne, Q. P. Avila, V. RYBENKOV, H. I. Zgurskaya, A. S. Duerfeldt

This study investigates how structural changes in oxazolidinones affect their permeation and activity in Gram-negative bacteria, identifying analogs with broad-spectrum activity.

bioRxiv · Jun 27, 2022Microbiology