Author

D. E. Wagner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Bioengineering· 1 Cancer Biology· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 6 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:drug response / drug discovery· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

G. T. Stathopoulos· 3 shared M. Vreka· 3 shared A. Marazioti· 2 shared I. Giopanou· 2 shared I. Lilis· 2 shared M. A. Pepe· 2 shared M. Lindner· 2 shared M. Spella· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPhysiology

G. T. Stathopoulos

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Modeling of Aberrant Epithelial Reprogramming in Idiopathic Pulmonary Fibrosis using Human Induced Pluripotent Stem Cell-derived Alveolar Organoids

V. Ptasinski, S. J. Monkley, K. Ost, M. Tammia, C. Overed-Sayer, P. Hazon, D. E. Wagner, L. A. Murray

This study develops a human iPSC-derived alveolar organoid model of IPF that recapitulates epithelial reprogramming and responds to antifibrotic drugs.

bioRxiv · Jun 15, 2022Cell Biology

Simultaneous isolation of proximal and distal lung progenitor cells from individual mice using a 3D printed guide reduces proximal cell contamination of distal lung epithelial cell isolations

H. N. Alsafadi, J. Stegmayr, V. Ptasinski, I. Silva, M. Mittendorfer, L. Murray, D. E. Wagner

This paper introduces a 3D-printed guide to isolate proximal and distal lung progenitor cells from mice, reducing contamination and improving the accuracy of in vitro assays.

bioRxiv · May 10, 2022Cell Biology

3D printed lung on a chip device with a stretchable nanofibrous membrane for modeling ventilator induced lung injury

S. Tas, E. Rehnberg, D. A. Bölükbas, J. P. Beech, L. Nasi Kazado, I. Svenningsson, M. Arvidsson, A. Sandberg, K. A. Dahlgren, A. Edthofer, A. Gustafsson, H. Isaksson, J. A. Wood, J. O. Tegenfeldt, D. E. Wagner

This paper develops a 3D printed lung-on-a-chip device with a stretchable nanofibrous membrane to model ventilator-induced lung injury by mimicking mechanical stretch and air-liquid interface conditions.

bioRxiv · Jul 2, 2021 · PreprintBioengineering

KRAS signalling in malignant pleural mesothelioma

A. Marazioti, A. Krontira, M. A. Pepe, M. Iliopoulou, D. E. Wagner, H. Papadaki, S. G. Antimisiaris, I. Psallidas, M. Spella, I. Lilis, I. Giopanou, M. Vreka, C. Blanquart, M. Gregoire, S. Deshayes, , G. T. Stathopoulos

This study identifies KRAS mutations as a significant driver in human malignant pleural mesothelioma and demonstrates their role in disease initiation and treatment response in mouse models.

bioRxiv · Oct 22, 2020 · PreprintPhysiology

Organ-restricted vascular delivery of nanoparticles for lung cancer therapy

D. A. Bolukbas, S. Datz, C. Meyer-Schwickerath, C. Morrone, A. Doryab, D. Goessl, M. Vreka, L. Yang, C. Argyo, S. H. van Rijt, M. Lindner, O. Eickelberg, T. Stoeger, O. Schmid, S. Lindstedt, , S. Meiners

This study introduces organ-restricted vascular delivery to enhance nanoparticle targeting to lung tumors, showing improved cellular uptake compared to systemic or intratracheal administration.

bioRxiv · Mar 5, 2020Pharmacology & Toxicology

Dual airway and alveolar contributions to adult lung homeostasis and carcinogenesis

M. Spella, I. Lilis, M. A. Pepe, Y. Chen, M. Armaka, A.-S. Lamort, D. E. Zazara, F. Roumelioti, M. Vreka, N. I. Kanellakis, D. E. Wagner, A. D. Giannou, V. Armenis, K. A. M. Arendt, L. V. Klotz, , G. T. Stathopoulos

This study identifies airway contributions to alveolar maintenance and lung adenocarcinoma development through mouse models and transcriptomic analysis.

bioRxiv · Jan 27, 2019Cancer Biology