Author

M. Turunen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Califano· 2 shared A. C. Iuga· 1 shared A. Curiel Garcia· 1 shared A. DeMarzo· 1 shared A. Griffin· 1 shared A. Hakkinen· 1 shared A. L. E. Wang· 1 shared A. Murgia· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

A. Califano

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Author profile →

4 papers

Recent·Most cited

Lineage-specific oncogenes drive growth of major forms of human cancer using common downstream mechanisms

O. Kauko, M. Turunen, P. Pihlajamaa, A. Hakkinen, R. M. Queiroz, M. Paakkonen, S. Ventela, M. Gaetani, S. Lundstrom, A. Murgia, B. Sahu, J. Routila, H. Irjala, J. L. Griffin, K. S. Lilley, , J. Taipale

The paper identifies common downstream mechanisms driven by lineage-specific oncogenes that regulate cell proliferation in various cancers.

bioRxiv · Sep 27, 2022 · PreprintCancer Biology

Systematic Elucidation and Pharmacological Targeting of Tumor-Infiltrating Regulatory T Cell Master Regulators

A. Obradovic, C. Ager, M. Turunen, T. Nirschl, M. Khosravi-Maharlooei, C. Jackson, V. Yegnasubramanian, A. DeMarzo, C. Kochel, M. Allaf, T. Bivalacqua, M. Lim, C. Karan, C. Drake, A. Califano

The paper identifies 17 master regulators of tumor-infiltrating regulatory T cells (TI-Tregs) and shows that targeting TRPS1 reduces tumor growth and enhances PD-1 inhibitor efficacy.

bioRxiv · Feb 22, 2022Cancer Biology

Developmental and MAPK-responsive transcription factors drive distinct malignant subtypes and genetic dependencies in pancreatic cancer

P. Laise, M. Turunen, A. Curiel Garcia, L. Tomassoni, C. Maurer, E. Elyada, B. Schmierer, J. Worley, J. Kesner, X. Tan, E. Calvo Fernandez, K. Wong, U. Wasko, S. Tagore, A. L. E. Wang, , A. Califano

The paper identifies three developmental lineages in pancreatic cancer driven by master regulators and shows their association with MAPK activity and therapeutic vulnerabilities.

bioRxiv · Oct 27, 2020 · PreprintCancer Biology

Diminishing effects of mechanical loading over time during rat Achilles tendon healing

H. Khayyeri, M. Hammerman, M. Turunen, P. Blomgran, T. Notermans, M. Guizar-Sicairos, P. Eliasson, H. Isaksson

This study examines how different loading magnitudes affect Achilles tendon healing in rats, finding early benefits of loading that diminish by 4 weeks.

bioRxiv · Jul 14, 2020Bioengineering