MSCs Successfully Deliver Oncolytic Virotherapy to Diffuse Intrinsic Pontine Glioma
M. Chastkofsky, K. C. Pituch, H. Katagi, L. Ilut, T. Xiao, Y. Han, A. M. Sonabend, D. T. Curiel, E. R. Bonner, J. Nazarian, C. Horbinski, C. D. James, A. Saratsis, R. Hashizume, M. S. Lesniak, I. V. Balyasnikova
This study shows that mesenchymal stem cells can deliver oncolytic virotherapy to DIPG tumors, significantly improving survival when combined with radiotherapy in preclinical models.
bioRxiv · May 9, 2020Cancer Biology