Author

A. M. Sonabend

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Mahajan· 2 shared C. Horbinski· 2 shared E. Gonzalez-Buendia· 2 shared L. Chen· 2 shared M. S. Lesniak· 2 shared T. Xiao· 2 shared A. Ahmed· 1 shared A. B. Heimberger· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

A. Mahajan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

H3.3-G34R Mutation-Mediated Epigenetic Reprogramming Leads to Enhanced Efficacy of Immune Stimulatory Gene Therapy in Diffuse Hemispheric Gliomas

M. B. Garcia Fabiani, S. Haase, K. Banerjee, Z. Zhu, B. McClellan, A. Mujeeb, Y. Li, C. E. Tronrud, M. L. Varela, M. E. J. West, J. Yu, P. Kadiyala, A. Taher, F. J. NUNEZ, M. S. Alghamri, , Sart

This study shows that H3.3-G34R mutations reprogram the tumor immune microenvironment in diffuse hemispheric gliomas, enhancing the efficacy of immune stimulatory gene therapy and leading to long-term survival in treated mice.

bioRxiv · Jun 13, 2023 · PreprintCancer Biology

MSCs Successfully Deliver Oncolytic Virotherapy to Diffuse Intrinsic Pontine Glioma

M. Chastkofsky, K. C. Pituch, H. Katagi, L. Ilut, T. Xiao, Y. Han, A. M. Sonabend, D. T. Curiel, E. R. Bonner, J. Nazarian, C. Horbinski, C. D. James, A. Saratsis, R. Hashizume, M. S. Lesniak, I. V. Balyasnikova

This study shows that mesenchymal stem cells can deliver oncolytic virotherapy to DIPG tumors, significantly improving survival when combined with radiotherapy in preclinical models.

bioRxiv · May 9, 2020Cancer Biology

CD8+ T-cell-mediated immunoediting influences genomic evolution and immune evasion in murine gliomas

J. R. Kane, J. Zhao, T. Tsujiuchi, B. Laffleur, A. Mahajan, G. Rao, A. Mela, C. Dmello, V. A. Arrieta, L. Chen, D. Y. Zhang, E. Gonzalez-Buendia, C. Lee-Chang, T. Xiao, G. Rothschild, , A. M. Sonabend

This study shows that CD8+ T-cells mediate immunoediting in murine gliomas, affecting genomic stability and immune evasion.

bioRxiv · Jul 16, 2019Cancer Biology

Interaction between DNA damage response, translation and apoptosome determines cancer susceptibility to TOP2 poisons

C. U. Awah, L. Chen, M. Bansal, A. Mahajan, J. Winter, M. Lad, L. Warnke, E. Gonzalez-Buendia, C. Park, D. Zhang, E. Feldstein, D. Yu, M. Zannikou, I. Balyasnikova, R. Martuscello, , A. M. Sonabend

The paper identifies genes involved in DNA damage response and translation that influence susceptibility to TOP2 poisons in gliomas and other cancers.

bioRxiv · Apr 25, 2019 · PreprintCancer Biology