Author

R. Hashizume

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1

Frequent Co-Authors

C. D. James· 2 shared T. Tomita· 2 shared A. M. Sonabend· 1 shared A. Mangoli· 1 shared A. Saratsis· 1 shared B. E. Foreman· 1 shared B. Mania-Farnell· 1 shared C. E. Stewart· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

C. D. James

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Ataxia-telangiectasia mutated (Atm) disruption sensitizes spatially-directed H3.3K27M/TP53 diffuse midline gliomas to radiation therapy

A. Mangoli, S. Wu, H. Q. Liu, M. Aksu, V. J. Jain, B. E. Foreman, J. A. Regal, L. B. Weidenhammer, C. E. Stewart, M. E. Guerra Garcia, E. Hocke, K. Abramson, N. T. Williams, L. Luo, K. Deland, , Z. J. Reitman

This study shows that disrupting ATM enhances radiation therapy efficacy in p53-mutant DMGs but not p53-wildtype DMGs using mouse models.

bioRxiv · Oct 18, 2023Cancer Biology

A red fluorescent genetically encoded biosensor for extracellular L-lactate

Y. Nasu, Y. Kamijo, R. Hashizume, H. Sato, Y. Hori, T. Tomita, M. Drobizhev, R. E. Campbell

The paper develops a red fluorescent biosensor for extracellular L-lactate, addressing spectral overlap issues of previous green biosensors.

bioRxiv · Aug 30, 2022 · PreprintBioengineering

WDR82 mediated H3K4me3 is associated with tumor proliferation and therapeutic efficacy in pediatric high-grade gliomas

N. Wadhwani, S. Nayak, Y. Wang, R. Hashizume, C. Jie, B. Mania-Farnell, C. D. James, G. Xi, T. Tomita

The paper shows that WDR82-mediated H3K4me3 promotes tumor proliferation and affects therapeutic response in pediatric high-grade gliomas.

bioRxiv · Mar 9, 2022Cancer Biology

MSCs Successfully Deliver Oncolytic Virotherapy to Diffuse Intrinsic Pontine Glioma

M. Chastkofsky, K. C. Pituch, H. Katagi, L. Ilut, T. Xiao, Y. Han, A. M. Sonabend, D. T. Curiel, E. R. Bonner, J. Nazarian, C. Horbinski, C. D. James, A. Saratsis, R. Hashizume, M. S. Lesniak, I. V. Balyasnikova

This study shows that mesenchymal stem cells can deliver oncolytic virotherapy to DIPG tumors, significantly improving survival when combined with radiotherapy in preclinical models.

bioRxiv · May 9, 2020Cancer Biology