Author

H. Kawai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Sugie· 1 shared B. M. Humbel· 1 shared C. Andoh· 1 shared C. Fujiwara· 1 shared G. Tavosanis· 1 shared H. Hori· 1 shared H. Kamiya· 1 shared H. Morishita· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperPathology

A. Sugie

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Transcriptional landscape of the dorsal raphe serotonin neurons rendering stress resiliency

C. Andoh, S. Otani, T. Noguchi, M. Hagiwara, N. Nishitani, H. Kawai, Y. Fukui, M. Koda, H. Morishita, K. Nomura, M. Oki, H. Hori, H. Shirakawa, S. Kaneko, K. Nagayasu

This study identifies gene expression changes in DRN serotonin neurons under antidepressant treatment and depression models, revealing S100a10 as a prodepressive gene and its regulatory pathway.

bioRxiv · Mar 21, 2024 · PreprintPharmacology & Toxicology

Systematic mutagenesis assay promotes comprehension of the strand-bias laws for mutations induced by oxidative DNA damage

H. Kawai, S. Ebi, R. Sugihara, C. Fujiwara, Y. Fujikawa, S. Kimura, H. Kamiya

This study uses a mutagenesis assay to show that single DNA lesions from oxidative damage can trigger strand-biased mutations at specific DNA sites.

bioRxiv · Feb 29, 2024Cell Biology

MeDUsA: A novel system for automated axon quantification to evaluate neuroaxonal degeneration

Y. Nitta, H. Kawai, J. Osaka, S. Hakeda-Suzuki, Y. Nagai, K. Doubkova, T. Suzuki, G. Tavosanis, A. Sugie

MeDUsA automates axon quantification in Drosophila to assess neuroaxonal degeneration, showing axonal degeneration occurs with ND-related proteins but not correlated with REP.

bioRxiv · Oct 25, 2021 · PreprintPathology

An interactive deep learning-based approach reveals mitochondrial cristae topologies

S. Suga, K. Nakamura, B. M. Humbel, H. Kawai, Y. Hirabayashi

The paper introduces a deep learning platform to analyze mitochondrial ultrastructure, revealing tubular cristae and a new role for OPA1 in cristae morphology.

bioRxiv · Jun 11, 2021 · PreprintCell Biology