S. Otani

Transcriptional landscape of the dorsal raphe serotonin neurons rendering stress resiliency

This study identifies gene expression changes in DRN serotonin neurons under antidepressant treatment and depression models, revealing S100a10 as a prodepressive gene and its regulatory pathway.

Global distribution and diversity of prevalent sewage water plasmidomes

This study analyzes global sewage plasmidomes to identify antimicrobial resistance genes and their distribution across bacterial hosts.

Detection of specific uncultured bacteriophages by fluorescence in situ hybridisation in pig microbiome

The paper detects specific uncultured bacteriophages in pig microbiomes using modified phageFISH and PCR, revealing their life cycle stages and demonstrating the first in vivo detection of jumbophages without culturing.

The oncogenic Runx3-Myc axis defines p53-deficient osteosarcomagenesis

This study identifies the Runx3-Myc axis as a driver of p53-deficient osteosarcomagenesis in human and mouse models.

A Peek into the Plasmidome of Global Sewage

This study analyzes the plasmidome of global sewage samples to identify plasmid-encoded traits, revealing novel plasmids and AMR gene distribution.

Gut microbial compositions mirror caste-specific diets in a major lineage of eusocial insects

The paper examines gut microbial compositions in fungus-growing termites, finding that caste-specific diets and division of labor correlate with distinct bacterial community structures.

Hemimetabolous genomes reveal molecular basis of termite eusociality

The paper compares genomes and transcriptomes of termites and cockroaches to identify molecular mechanisms underlying termite eusociality, finding parallels and differences with Hymenoptera.