Drosophila model to clarify the pathological significance of OPA1 in autosomal dominant optic atrophy
Y. Nitta, J. Osaka, R. Maki, S. Hakeda-Suzuki, E. Suzuki, S. Ueki, T. Suzuki, A. Sugie
This study uses a Drosophila model to distinguish between loss-of-function and dominant negative OPA1 mutations in DOA and DOA plus.
bioRxiv · Mar 17, 2023Pathology