Author

H. Lachuer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Assay:imaging· 2 Organism:mouse· 2

Frequent Co-Authors

B. Goud· 3 shared K. Schauer· 3 shared A. D. Baffet· 1 shared A. Hirschler· 1 shared A. Larnicol· 1 shared A. Molitor· 1 shared A. Mousson· 1 shared A. Pichot· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCell Biology

B. Goud

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Collective directional memory controls the range of epithelial cell migration

H. Canever, H. Lachuer, Q. Delaunay, F. Sipieter, N. Auduge, P. P. Girard, N. Borghi

The paper shows that epithelial cells exhibit superdiffusive migration in tissues due to directional memory from velocity coordination and adhesion dynamics, enhancing their range compared to isolated cells.

bioRxiv · Dec 8, 2023 · PreprintBiophysics

Peripheral positioning of lysosomes supports melanoma aggressiveness

K. Jerabkova-Roda, A. Mousson, M. Peralta, R. Karali, H. Justiniano, L.-M. Lisii, P. Carl, N. Asokan, I. Busnelli, A. Larnicol, O. Lefebvre, H. Lachuer, A. Pichot, T. Stemmelen, A. Molitor, , K.-J. Huang

This study shows that lysosomal positioning in melanoma cells correlates with aggressiveness, promoting invasion and matrix degradation.

bioRxiv · Jul 7, 2023Cell Biology

Membrane tension spatially organizes lysosomal exocytosis

H. Lachuer, L. Le, S. Leveque-fort, B. Goud, K. Schauer

This study shows that lysosomal exocytosis clusters spatially at the plasma membrane of RPE1 cells, driven by membrane tension patterns controlled by focal adhesions.

bioRxiv · Apr 22, 2022 · PreprintBiophysics

Regulation of neuronal progenitor delamination by dynein-driven post-Golgi apical transport

J.-B. Brault, S. Bardin, M. Lampic, J. Carpentieri, L. Coquand, M. Penisson, H. Lachuer, G. S. Victoria, S. Baloul, G. Boncompain, S. Miserey-Lenkei, V. Fraisier, F. Francis, F. Perez, B. Goud, A. D. Baffet

This study identifies a RAB6-dynein-LIS1 complex that regulates apical transport in radial glial cells, essential for maintaining neuroepithelial integrity and proper brain development.

bioRxiv · Jul 23, 2021 · PreprintCell Biology

Transcription Factor EB regulates phosphatidylinositol-3-phosphate levels on endomembranes and alters lysosome positioning in the bladder cancer model

P. Mathur, C. De Barros Santos, H. Lachuer, B. Latge, F. Radvanyi, B. Goud, K. Schauer

This study identifies TFEB's role in regulating PtdIns3P levels and lysosome positioning in bladder cancer, suggesting it as a potential biomarker and therapeutic target.

bioRxiv · Jul 10, 2020 · PreprintCell Biology