Author

H. Le Hir

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:spatial transcriptomics· 3 Research Focus:cell signaling & trafficking· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. SAFIEDDINE· 3 shared E. BERTRAND· 3 shared E. COLENO· 3 shared O. S. KWON· 3 shared A.-M. Traboulsi· 2 shared K. Zibara· 2 shared M. Peter· 2 shared M.-C. Robert· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

A. SAFIEDDINE

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Author profile →

4 papers

Recent·Most cited

Identification of an evolutionary conserved binding motif responsible for the recruitment of NMD factors to the UPF1 helicase

I. Barbarin-Bocahu, N. Ulryck, A. Rigobert, N. Ruiz Gutierrez, L. Decourty, M. Raji, B. Garkhal, H. Le Hir, C. Saveanu, M. Graille

The paper identifies a conserved binding motif in Nmd4 that interacts with Upf1, showing its role in NMD and conservation in metazoan SMG6.

bioRxiv · Feb 27, 2024 · PreprintBiochemistry

Exon Junction Complex dependent mRNA localization is linked to centrosome organization during ciliogenesis

O. S. KWON, R. K. MISHRA, A. SAFIEDDINE, Q. ALASSEUR, M. FAUCOURT, E. COLENO, I. BARBOSA, E. BERTRAND, N. SPASSKY, H. LE HIR

The paper shows EJC-dependent mRNA localization to centrosomes affects ciliogenesis and mNSC division.

bioRxiv · Oct 28, 2020Cell Biology

A conserved choreography of mRNAs at centrosomes reveals a localization mechanism involving active polysome transport

A. Safieddine, E. Coleno, A.-M. Traboulsi, O. S. Kwon, F. Lionneton, V. Georget, M.-C. Robert, T. Gostan, C. Lecellier, S. Salloum, R. Chouaib, X. Pichon, H. Le Hir, K. Zibara, M. Peter, E. Bertrand

The paper identifies conserved centrosomal mRNAs that localize via active polysome transport mediated by nascent proteins, using human and Drosophila models.

bioRxiv · Sep 4, 2020Cell Biology

A localization screen reveals translation factories and widespread co-translational RNA targeting

R. Chouaib, A. SAFIEDDINE, X. Pichon, A. Imbert, O. S. Kwon, A. Samacoits, A.-M. Traboulsi, M.-C. Robert, N. Tsanov, E. Coleno, I. Poser, C. Zimmer, A. A. Hyman, H. Le Hir, K. Zibara, , E. Bertrand

The paper identifies translation factories and co-translational RNA targeting through a dual protein/mRNA localization screen in human cells.

bioRxiv · May 20, 2020Cell Biology