M. Faucourt

Cyclin O controls entry into the cell-cycle variant required for multiciliated cell differentiation

Cyclin O is necessary for multiciliated cells to enter their differentiation cell cycle variant and allows the massive amplification of centrioles, which serve as basal bodies for cilia nucleation.

Identification of a new cell cycle variant during multiciliated cell differentiation

The paper identifies a new cell cycle variant in multiciliated cells that enables centriole amplification without DNA replication or mitosis.

The cell cycle variant in multiciliated cells incorporates 2 centriole biogenesis cycles

This study shows the MCC cell cycle variant accelerates centriole biogenesis by overlapping two cycles to produce multiple mature centrioles without cell division.

Exon Junction Complex dependent mRNA localization is linked to centrosome organization during ciliogenesis

The paper shows EJC-dependent mRNA localization to centrosomes affects ciliogenesis and mNSC division.

Synchronization of mammalian motile cilia in the brain with hydrodynamic forces

The paper shows that hydrodynamic forces between cilia in brain cells can synchronize their beating, with fewer cilia per cell being more responsive to external flows.

Dynamics of centriole amplification in centrosome-depleted brain multiciliated progenitors

The paper investigates centriole amplification in centrosome-depleted brain multiciliated progenitors, showing amplified centrioles originate from the daughter centriole and not de novo.