Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
W. Wang, Y. Zhou, J. Wang…·K. P. Nephew
This study shows that inhibiting HOTAIR and EZH2 reduces ovarian cancer stem cell resistance to platinum chemotherapy and improves survival in vivo.
A. H. Ghobashi, T. T. Vuong, J. W. Kimani, H. M. O'Hagan
This study shows that AKT activation in colorectal cancer leads to EZH2-mediated beta-catenin methylation, enhancing gene expression and promoting tumor progression.
V. Muralikrishnan, F. Fang, T. C. Given…·K. P. Nephew
This study identifies a novel ALDH1A1 inhibitor that suppresses chemotherapy-induced senescence and stemness in ovarian cancer stem cells, suggesting its potential for clinical use.
R. Sood, S. Sriramkumar, V. Muralikrishnan…·H. M. O'Hagan
This study shows that combining DNMT and NAMPT inhibitors with platinum reduces OCSCs and tumorigenesis in ovarian cancer.
S. Sriramkumar, T. D. Matthews, A. H. Ghobashi…·H. M. O'Hagan
This study identifies RING1A-mediated ubiquitination of phosphorylated H2AX at platinum DNA damage sites in ovarian cancer, revealing its role in DNA repair and platinum resistance.
S. A. Miller, R. A. Policastro, S. Sriramkumar…·H. M. O'Hagan
The paper identifies LSD1 as a regulator of secretory cell specification in BRAF-mutant colorectal cancer, showing its role in tumor growth and metastasis.