A CUG-initiated CATSPERθ functions in the CatSper channel assembly and serves as a checkpoint for flagellar trafficking
X. Huang, H. Miyata, H. Wang, G. Mori, R. Iida-Norita, M. Ikawa, R. Percudani, J.-J. Chung
This study identifies CATSPER{theta} as essential for CatSper channel assembly in sperm flagella, revealing its role in channel formation and flagellar trafficking, leading to male infertility in its absence.
bioRxiv · Mar 17, 2023Cell Biology