Author

H. Okkenhaug

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. Oxley· 2 shared S. Walker· 2 shared A. Anwar· 1 shared A. Kielkowska· 1 shared A. Segonds-Pichon· 1 shared B. A. Sadiq· 1 shared D. Barneda· 1 shared D. J. Benton· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

D. Oxley

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A cyclic peptide toolkit reveals mechanistic principles of peptidylarginine deiminase IV (PADI4) regulation

M. T. Bertran, R. Walmsley, T. F. M. Cummings, I. Aramburu, D. J. Benton, J. Assalaarachchi, M. Chasampalioti, T. Swanton, D. Joshi, S. Federico, H. Okkenhaug, L. Yu, D. Oxley, S. Walker, V. Papayannopoulos, , L. J. Walport

The paper develops cyclic peptide modulators of PADI4 and reveals their mechanism of action and cellular activity.

bioRxiv · Dec 12, 2023Biochemistry

PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate

T. A. M. Chessa, P. Jung, S. Suire, A. Anwar, K. E. Anderson, D. Barneda, A. Kielkowska, B. A. Sadiq, D. Oxley, S. Felisbino, D. Spensberger, A. Segonds-Pichon, M. Wilson, S. Walker, H. Okkenhaug, , L. R. Stephens

The paper identifies PLEKHS1 as a driver of PI3K activity in PTEN-null prostate tissue, showing it bypasses feedback mechanisms to promote tumour progression.

bioRxiv · May 18, 2023Cell Biology

Follicular regulatory T cells can access the germinal centre independently of CXCR5

I. Vanderleyden, S. Fra-Bido, S. Innocentin, H. Okkenhaug, N. Evans-Bailey, W. Pierson, M. Linterman

This study shows that follicular regulatory T cells can access the germinal centre without CXCR5, indicating CXCR5-independent mechanisms for their homing.

bioRxiv · May 17, 2019Immunology