B cells from aged mice do not have intrinsic defects in affinity maturation
J. L. Lee, S. Innocentin, A. Silva-Cayetano, S. Guillaume, M. A. Linterman
This study shows that B cells from aged mice can undergo affinity maturation similarly to young B cells when their receptor repertoire is constant.
bioRxiv · Apr 24, 2023 · PreprintImmunology