Author

H. Permentier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

S. El Aidy· 2 shared A. Keshavarzian· 1 shared H. R. de Jong· 1 shared J. Aresti· 1 shared R. R. Pereira· 1 shared S. A. Nelemans· 1 shared S. L. Winkel· 1 shared S. P. van Kessel· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

S. El Aidy

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Author profile →

2 papers

Recent·Most cited

pH-dependent spontaneous hydrolysis rather than gut bacterial metabolism reduces levels of the ADHD treatment, Methylphenidate

J. Aresti, W. Maho, R. R. Pereira, H. Permentier, S. El Aidy

This study shows that pH-dependent spontaneous hydrolysis, not gut bacterial metabolism, reduces methylphenidate levels, affecting its bioavailability.

bioRxiv · Jul 6, 2020 · PreprintMicrobiology

Gut bacterial deamination of residual levodopa medication for Parkinson's disease

S. P. van Kessel, H. R. de Jong, S. L. Winkel, S. S. van Leeuwen, S. A. Nelemans, H. Permentier, A. Keshavarzian, S. El Aidy

This study shows that gut bacteria deaminate levodopa, a Parkinson's disease medication, and identifies the enzyme responsible, with implications for drug effectiveness and side effects.

bioRxiv · Feb 13, 2020Microbiology