Gut bacterial deamination of residual levodopa medication for Parkinson's disease
S. P. van Kessel, H. R. de Jong, S. L. Winkel, S. S. van Leeuwen, S. A. Nelemans, H. Permentier, A. Keshavarzian, S. El Aidy
This study shows that gut bacteria deaminate levodopa, a Parkinson's disease medication, and identifies the enzyme responsible, with implications for drug effectiveness and side effects.
bioRxiv · Feb 13, 2020Microbiology