Author

S. P. van Kessel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:metagenomics· 1

Frequent Co-Authors

S. El Aidy· 2 shared A. Bullock· 1 shared A. Domenech· 1 shared A. Keshavarzian· 1 shared C. Gallay· 1 shared G. van Dijk· 1 shared H. Permentier· 1 shared H. R. de Jong· 1 shared

Activity by Year

2016-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

S. El Aidy

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Author profile →

3 papers

Recent·Most cited

MicrobiologybioRxivJul 19, 2021

Parkinson' disease medication alters rat small intestinal motility and microbiota composition

S. P. van Kessel, A. Bullock, G. van Dijk, S. El Aidy

This study shows that Parkinson's disease medications reduce small intestinal motility and alter microbiota composition in rats, mirroring human PD microbiota changes.

DOI 10.1128/msystems.01191-21

ratmetagenomics

𝕏 PostBluesky

MicrobiologybioRxivFeb 13, 2020

Gut bacterial deamination of residual levodopa medication for Parkinson's disease

S. P. van Kessel, H. R. de Jong, S. L. Winkel…·S. El Aidy

This study shows that gut bacteria deaminate levodopa, a Parkinson's disease medication, and identifies the enzyme responsible, with implications for drug effectiveness and side effects.

DOI 10.1186/s12915-020-00876-3

humanmetabolomics

𝕏 PostBluesky

MicrobiologybioRxivNov 17, 2016

High-throughput CRISPRi phenotyping in Streptococcus pneumoniae identifies new essential genes involved in cell wall synthesis and competence development

X. Liu, C. Gallay, M. Kjos…·J.-W. Veening

This study uses CRISPRi to identify essential genes in S. pneumoniae, revealing roles in cell wall synthesis and competence development, and highlights potential antibiotic targets.

DOI 10.15252/msb.20167449

non-human primategenetic perturbation / CRISPR

𝕏 PostBluesky