Multi-site phosphorylation of the TOPBP1 ATR Activation Domain propels ATR signaling during the response to DNA breaks
H. Senebandith, K. Ruis, K. Montales, O. Huynh, Y. Jami-Alahmadi, J. Wohlschlegel, W. M. Michael
This study identifies multi-site phosphorylation of the TOPBP1 ATR activation domain as critical for ATR activation during DNA damage response.
bioRxiv · Sep 19, 2022 · PreprintCell Biology