H. Sha

AutoUnmix: an autoencoder-based spectral unmixing method for multi-color fluorescence microscopy imaging

AutoUnmix is a deep learning-based spectral unmixing method for multi-color fluorescence microscopy that outperforms existing methods in speed and accuracy.

Deep learning-enhanced single-molecule spectrum imaging

This paper introduces SpecGAN, a deep learning method that significantly improves single-molecule spectrum imaging efficiency by reducing photon requirements and increasing temporal resolution.

Germline Selection by Meiosis Defends the Transmission of defective Mitochondria with mtDNA variants

The paper investigates mtDNA variants in human polar bodies and mouse oocytes, showing meiotic selection removes defective mitochondria.

Suppression of Docetaxel induced apoptosis in Survivin-depleted cells due to failure of sustained mitotic block

This study shows that Survivin depletion in cells leads to evasion of Docetaxel-induced mitotic block and apoptosis, increasing mitotic catastrophe and senescence, thereby enhancing drug efficacy.

Inhibitor of the spindle assembly checkpoint surpasses apoptosis sensitizer in synergy with taxanes

This study shows that inhibiting the spindle assembly checkpoint (SAC) is more effective than apoptosis sensitizers in enhancing taxane-induced tumor cell growth arrest.