H. Shi

The paper introduces HiPR-FISH, a method to map microbial communities with high spatial and taxonomic resolution, demonstrating its ability to distinguish multiple E. coli strains and reveal spatial structures in human and mouse microbiomes.

This study identifies AimB as a small protein that inhibits MreB polymerization in Caulobacter crescentus, leading to altered cell shape and MreB delocalization.

This study identifies PD-1 palmitoylation, its regulatory enzyme, and develops a peptide inhibitor to target PD-1 expression for cancer immunotherapy.

This study identifies and validates a novel QTL on chromosome 6HL in barley that confers resistance to Fusarium crown rot, explaining 29.1% of phenotypic variance.

This study shows NAD+ increases antioxidant capacity in PC12 cells through SIRT2, ERK, and Nrf2 pathways under basal conditions.

This study shows that left-handed twisting in MreB filaments, influenced by nucleotide and membrane binding, determines filament length and orientation in Caulobacter crescentus.

This study uses molecular dynamics simulations to analyze conformational dynamics of four prokaryotic actin homologs, revealing nucleotide-dependent and -independent behaviors and their implications for filament structure regulation.

This study shows that E. coli regulates cell width by modulating RodZ and MreB to control cell-wall insertion patterns.